U.S. kicks off clinical trial of antiviral chemical to treat COVID-19

2020-02-26 10:15:58Xinhua Editor : Li Yan ECNS App Download
Special: Battle Against Novel Coronavirus

A randomized, controlled clinical trial has begun at the University of Nebraska Medical Center (UNMC) in Omaha, the United States, to evaluate the safety and efficacy of the investigational antiviral remdesivir in hospitalized adults diagnosed with COVID-19.

The U.S. National Institutes of Health (NIH) announced on Tuesday that the first trial participant is an American who was repatriated after being quarantined on the Diamond Princess cruise ship that docked in Japan and volunteered to participate in the study.

Clinical trials of remdesivir are also ongoing in China where more than 200 patients with severe and critical symptoms and over 30 patients with mild and common symptoms have been enrolled in the trial.

At least one COVID-19 patient in the United States had used the compound for a treatment via Compassionate Use approved by the U.S. Food and Drug Administration (FDA).

Currently, there are no specific therapeutics approved by the FDA to treat people with COVID-19.

Remdesivir is an investigational broad-spectrum antiviral treatment. Initially developed against Ebola infections by American pharmaceutical company Gilead Sciences, it has shown fairly good antiviral activity against the novel coronavirus at the cellular level.

"A randomized, placebo-controlled trial is the gold standard for determining if an experimental treatment can benefit patients," said Anthony S. Fauci, director of National Institute of Allergy and Infectious Diseases under the NIH.


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