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World's largest pork producer is exploring ways to grow human organs from pig parts(2)

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2017-05-08 14:49China Daily Editor: Yao Lan ECNS App Download

Stanton says the company plans to look into ways all types of major organs and skin could be used for transplants.

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"There are striking similarities between pigs and humans: for example, our DNA and digestive tract," she says.

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More than 118,000 Americans are on the waiting list for organ transplants, and approximately 22 people die each day waiting on new organs, according to the US Health Resources and Services Administration.

ÃÀ¹úÎÀÉú×ÊÔ´ºÍ·þÎñ¹ÜÀí¾Ö±íʾ,µÈºòÆ÷¹ÙÒÆÖ²µÄÃÀ¹úÈËÊýÁ¿³¬¹ý11.8Íò,¶øÿÌì´óÔ¼ÓÐ22ÈËÒòδµÈµ½ÐÂÆ÷¹Ù¶øÈ¥ÊÀ.

In 2016, doctors performed a record-high 33,500 transplants.

2016Äê,Ò½ÉúÃÇ×ܹ²Ö´ÐÐÁË33500´ÎÒÆÖ²ÊÖÊõ,´òÆÆÁËÀúÊ·¼Ç¼.

The largest hurdle for pig-human organ transplants is the fact that pigs have genes encoded with viruses that could transmit diseases to humans.

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A second challenge is immunology - if doctors were to introduce a pig organ to the human body, the immune system might reject the organ and attack it.

µÚ¶þ¸öÌôÕ½ÊÇÃâÒß·´Ó¦,Èç¹ûÒ½ÉúÒª½«ÖíÆ÷¹ÙÒÆÖ²µ½ÈËÌåÄÚ,ÈËÀàµÄÃâÒßϵͳ¿ÉÄÜ»áÅųⲢ¹¥»÷Æ÷¹Ù.

Smithfield, a US$14 billion subsidiary of the Chinese meat processing giant WH Group, already gathers and sells pig parts, like pancreases and thyroid glands, for a variety of medical purposes.

Ê·ÃÜ˹·Æ¶ûµÂ¹«Ë¾ÊÇÖйúÈâÀà¼Ó¹¤¾ÞÍ·Ë«»ã¼¯ÍŵÄÒ»¸ö¼ÛÖµ140ÒÚÃÀÔªµÄ×Ó¹«Ë¾,ÒѾ­¿ªÊ¼ÊÕ¼¯ºÍÏúÊÛÖíµÄÆ÷¹Ù£¨ÈçÒÈÏٺͼ××´ÏÙ£©,ÒÔÓÃÓÚ¸÷ÖÖÒ½ÁÆÓÃ;.

The US market for pork materials - for medical, pet food, and non-food purposes - totals over US$100 billion.

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Most of the pork materials Smithfield sells are used to make ingredients in drugs that treat conditions like indigestion and hypothyroidism.

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For example, the company supplies mucosa (a hog's intestinal membrane) to healthcare companies to create Heparin, a blood thinner that prevents clotting in surgeries. The parts have not yet been used to develop human cells, however.

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While Smithfield is one of the largest companies venturing into pig-human transplants, it's not alone. Biotech startup Egenesis, which raised US$38 million in March, uses a gene-editing tool to make pig organs viable for transplants.

ËäȻʷÃÜ˹·Æ¶ûµÂ¹«Ë¾ÊÇÑо¿ÓÃÓÚÈËÀàÒÆÖ²µÄÖíÆ÷¹ÙµÄ×î´óµÄÆóÒµÖ®Ò»,µ«»¹ÓÐÆäËû¹«Ë¾Ô¾Ô¾ÓûÊÔ.3ÔÂ,ÉúÎï¿Æ¼¼´´Òµ¹«Ë¾EgenesisÒѾ­ÈÚ×Ê3800ÍòÃÀÔª,¸Ã¹«Ë¾²ÉÓûùÒò±à¼­¹¤¾ß´¦ÀíÖíµÄÆ÷¹Ù,ʹÆäÄܹ»ÓÃÓÚÒÆÖ².

The regenerative medicine company Revivicor is also breeding pigs that have some genetic similarities to humans on a Virginia farm. The team has added five human genes to the pigs' livers, kidneys, and hearts.

ÔÙÉúҽѧ¹«Ë¾RevivicorÒ²ÔÚ×öÀàËƵÄÑо¿,¸Ã¹«Ë¾ÔÚ¸¥¼ªÄáÑǵÄÒ»¸öÅ©³¡ÅàÓýÓëÈËÀà¾ßÓÐÒÅ´«ÏàËÆÐÔµÄÖí.ÍŶÓÒѾ­³É¹¦µØÏòÖíµÄ¸ÎÔà¡¢ÉöÔàºÍÐÄÔà¼ÓÈëÁËÎå¸öÈËÀà»ùÒò.

Stanton says her team anticipates a learning curve as Smithfield attempts to harness these new technologies.

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"Although we are still in the infancy stage of this new research, we hope to provide elements that will help to facilitate a variety of organ transplants and injury recovery solutions in the future," she says.

"ËäÈ»ÕâÏîÐÂÑо¿»¹´¦ÓÚ³õ¼¶½×¶Î,µ«ÊÇÎÒÃÇÏ£ÍûÄܹ»³öÒ»·ÝÁ¦,ÒÔ´Ù½øδÀ´¸÷ÖÖÆ÷¹ÙÒÆÖ²ºÍËðÉ˻ָ´½â¾ö·½°¸µÄ²úÉú."Ëý˵.

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